CD58 Polyclonal Antibody, 50ul[BT-AP02432] Roller Bottles Expression of this protein is

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

A related pseudogene has been identified on chromosome 7

interleukin 3 regulated encoded by NFIL3 is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters

The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites

An important paralog of this gene is SLC38A1

CD58 Polyclonal Antibody, 50ul[BT-AP02432] Roller Bottles Expression of this protein isCYP7B1 (cytochrome P450 family 7 subfamily B member 1) encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile