53BP1 Polyclonal Antibody, 50ul[BT-AP00042] In vitro Assessment SNAPC5 encodes a subunit of

SNAPC5 encodes a subunit of the small nuclear RNA (snRNA)-activating protein complex that plays a role in the transcription of snRNA genes

A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene

This kinase contains a SH3 domain and a leucine zipper-basic motif

tissue specificity:B-cell specific

in bladder and lung carcinomas

53BP1 Polyclonal Antibody, 50ul[BT-AP00042] In vitro Assessment SNAPC5 encodes a subunit ofThe p53 binding proteins 53BP1 and 53BP2 (Bbp) bind to the central DNA binding domain of wild type p53, but do not bind mutant p53. The central DNA binding domain of p53 is required for site specific DNA binding and is frequently mutated in malignant tumors. Binding of 53BP1 to the L3 loop of p53 and of 53BP2 to the L2 loop of p53 confirms that the loop is dependent on p53 conformation. Site specific binding also suggests that 53BP1 and 53BP2 are