Arrestin-C Polyclonal Antibody, 100ul ADME Humans have six elastase genes

Humans have six elastase genes which encode the structurally similar proteins elastase 1

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and Deafness)

Mutations in this gene cause familial hypocalciuric hypercalcemia

It also acts as a coreceptor for various SIV strains and for a primary HIV-1 strain

Arrestin-C Polyclonal Antibody, 100ul ADME Humans have six elastase genesThe protein encoded by ARR3 is a non visual arrestin which binds to agonist activated, phosphorylated G protein coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma tubulin to help regulate proper centrosome function.