RANKL Polyclonal Antibody, 100ul[BT-AP07786] Immunoassays Exportin 1 also regulates NFAT

Exportin 1 also regulates NFAT and AP-1

Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation

together with other proteins

2 that encodes a component of the HBO1 complex which is responsible for the bulk of histone H4 acetylation

where it is differentially expressed during differentiation

RANKL Polyclonal Antibody, 100ul[BT-AP07786] Immunoassays Exportin 1 also regulates NFATThis gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss.