ANO5 Rabbit Polyclonal Antibody, 50ul ADME Phosphorylates CTNNB1 at Ser-45

Phosphorylates CTNNB1 at Ser-45

May exert this function by promoting GLI1 nuclear localization

The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region

some of which are tissue-specific

which may play a role in the signal transduction pathway mediated by multiple Wnt proteins

ANO5 Rabbit Polyclonal Antibody, 50ul ADME Phosphorylates CTNNB1 at Ser-45This gene encodes a member of the anoctamin family of transmembrane proteins. The encoded protein is likely a calcium activated chloride channel. Mutations in this gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described.