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HLA Class I Polyclonal Antibody, 100ul[BT-AP10061] Pipette Micro Tips It is suggested that this

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HLA Class I Polyclonal Antibody, 100ul[BT-AP10061] Pipette Micro Tips It is suggested that thisHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon

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It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1

ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization

and it plays an important role in the signaling cascades leading to insulin secretion

A mutation in this gene has been reported to be associated with hereditary spastic paraplegia| however the pathogenicity of the mutation| which may simply represent a polymorphism| is unclear

CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating

HLA Class I Polyclonal Antibody, 100ul[BT-AP10061] Pipette Micro Tips It is suggested that thisHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon

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