PMS2/PMS2CL Polyclonal Antibody, 20ul Purification Several transcript variants encoding distinct

Several transcript variants encoding distinct isoforms have been identified for this gene

DLX5 encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene

suggests a specific function in bone development and maintenance

induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins

ADGRE3 is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19

PMS2/PMS2CL Polyclonal Antibody, 20ul Purification Several transcript variants encoding distinctThe protein encoded by PMS2 (PMS1 homolog 2, mismatch repair system component) is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL alpha heterodimer. The MutL alpha heterodimer possesses an endonucleolytic