Human Thioredoxin-interacting Protein, TXNIP ELISA Kit , 96T Adenovirus Packaging Involved in ubiquitination of IGF1R

Involved in ubiquitination of IGF1R

Txk expression is T cell-specific

The G-protein signaling modulator 1 contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half

Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2

Plays a role in enhancing learning and memory performance (By similarity)

Human Thioredoxin-interacting Protein, TXNIP ELISA Kit , 96T Adenovirus Packaging Involved in ubiquitination of IGF1RMay act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5 induced suppression of CDKN1B stability, blocking the COPS5 mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over expression will induce G0 G1