TIRAP Polyclonal Antibody, 100ul Monoclonal Antibodies The product of this gene

The product of this gene belongs to the family of P2 receptors

Alteration of this gene is implicated in the pathogenetics of schizophrenia

PubMed: 21050863

tissue specificity:Highly expressed in kidney

and may also have a role in immune tolerance at the maternal-fetal interface

TIRAP Polyclonal Antibody, 100ul Monoclonal Antibodies The product of this geneThe innate immune system recognizes microbial pathogens through Toll like receptors (TLRs), which identify pathogen associated molecular patterns. Different TLRs recognize different pathogen associated molecular patterns and all TLRs have a Toll interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The TIR domain containing adaptor protein encoded by TIRAP is a TIR adaptor protein involved in the TLR4 signaling pathway of