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OGFR Polyclonal Antibody, 20ul Cell Transfection Three transcript variants encoding two

SKU: 21407938263

4.9
SEK97.20 SEK121.20

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OGFR Polyclonal Antibody, 20ul Cell Transfection Three transcript variants encoding twoThe opioid growth factor receptor encoded by OGFR is a receptor for opioid growth factor (OGF), also known as [Met(5)] enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem

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Description

Three transcript variants encoding two different isoforms have been found for this gene

This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids

Methylation of the promoter of CEBPZ or mutations within CEBPZ may be correlated with occurance of acute myeloid leukemia (AML)

Loss of function of EPN1 is associated with reduced tumor growth and progression in certain cancer types

The growth factor receptor bound protein 2 encoded by GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains

OGFR Polyclonal Antibody, 20ul Cell Transfection Three transcript variants encoding twoThe opioid growth factor receptor encoded by OGFR is a receptor for opioid growth factor (OGF), also known as [Met(5)] enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem

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