GIT1 Polyclonal Antibody, 50ul Adenovirus Packaging Multiple pseudogenes that map to

Multiple pseudogenes that map to different chromosomes have been reported

This gene is highly expressed in brain and heart

Cyclin dependent kinase 5 regulatory subunit 2 and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins

and may be oncogenic

The encoded protein localizes to the plasma membrane

GIT1 Polyclonal Antibody, 50ul Adenovirus Packaging Multiple pseudogenes that map toARF GTPase activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. GIT1 contains an ARFGAP domain, Anykrin repeats and a GRK interacting domain. The Arf GAP domain, which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases, has been shown to be involved in phosphorylation and inhibition of the ADRB2. If synaptic localization of GIT1 is disturbed, then this is known to affect dendritic spine