Vav(Phospho Tyr160) Polyclonal Antibody, 50ul Cell fragmentation and collection BCL2 associated agonist of cell

BCL2 associated agonist of cell death positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2

The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that TESK1 plays an important role at and after the meiotic phase of spermatogenesis

It is also expressed in specific regions of the brain

This gene is highly expressed in fetal tissues and at lower levels in few adult tissues| thus may function in signaling pathways utilized broadly during fetal development| and more selectively in adult tissues

SLC8 subfamily

Vav(Phospho Tyr160) Polyclonal Antibody, 50ul Cell fragmentation and collection BCL2 associated agonist of cellThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.