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p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11730] Cryopreservation Alternative splicing results in transcript

SKU: 20995069522

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PLN185.00 PLN222.00

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p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11730] Cryopreservation Alternative splicing results in transcriptThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

Alternative splicing results in transcript variants encoding distinct isoforms

Mothers against decapentaplegic homolog 5 encoded by SMAD5 is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells

short-time run function

An important paralog of this gene is SFT2D1

The protein encoded by this gene binds to CLP1 to form pre-mRNA cleavage factor IIm

p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11730] Cryopreservation Alternative splicing results in transcriptThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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