DYRK2 Polyclonal Antibody, 20ul Site-directed Mutagenesis Exogenous expression of this gene

Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells

RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al

A mutation in this gene results in nonsyndromic mental retardation-3

at intermediate levels in kidney and placenta and at lowest levels in brain

and the transcription factors ATF2 (activating transcription factor 2) and c-JUN

DYRK2 Polyclonal Antibody, 20ul Site-directed Mutagenesis Exogenous expression of this geneDYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1,