RNase Z2 Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene have
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RNase Z2 Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene haveThe protein encoded by ELAC2 (elaC ribonuclease Z 2) has a C terminal domain with tRNA processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST 1), and reduced expression can suppress transforming growth factor beta induced growth arrest. Mutations in ELAC2 result in an
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