IRS-1 Polyclonal Antibody, 100ul[BT-AP04647] Purification it consists of a 35-kD

it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520)

cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits

NCK2 (NCK adaptor protein 2) encodes a member of the NCK family of adaptor proteins

IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane

The encoded protein is a brain-specific inhibitor of angiogenesis

IRS-1 Polyclonal Antibody, 100ul[BT-AP04647] Purification it consists of a 35-kDIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.