Rat Uromodulin, UMOD ELISA Kit, 96T Diagnostic Probes & Oligos This gene has a mouse

This gene has a mouse ortholog

two chain form held together by a disulfide bond

It functions in the cardiovascular and central nervous systems

GO annotations related to this gene include bile acid: sodium symporter activity

of human breast cancer and melanoma cell lines

Rat Uromodulin, UMOD ELISA Kit, 96T Diagnostic Probes & Oligos This gene has a mouse[Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL 1, IL 2) and TNF. Facilitates neutrophil migration across renal epithelia. [Uromodulin, secreted form]: In the