ATG10 Polyclonal Antibody, 100ul Immune Cell Preparation The product of this gene

The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes

This protein is part of the COPII coat complex

but is also expressed in liver

Recurrent rearrangements of this gene with the Ewing's sarcoma gene

Alternatively spliced transcript variants have also been noted for this gene

ATG10 Polyclonal Antibody, 100ul Immune Cell Preparation The product of this geneAutophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2 like enzyme involved in 2 ubiquitin like modifications essential for autophagosome formation: ATG12 (MIM 609608) ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane bound form (Nemoto et al., 2003