Rb(Phospho Thr821) Polyclonal Antibody, 100ul Adenovirus Packaging neurophysin 2 and copeptin

neurophysin 2 and copeptin

Upon growth factor induction of quiescent cells

RIOK1 (RIO kinase 1) includes two alternatively spliced transcript variants

Isoforms are also integral to development

The encoded protein consists of an extracellular domain containing seven cadherin repeats

Rb(Phospho Thr821) Polyclonal Antibody, 100ul Adenovirus Packaging neurophysin 2 and copeptinThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.