14-3-3 Beta Polyclonal Antibody, 50ul[BT-AP00004] Roller Bottles Contains 27 C2H2-type zinc fingers

Contains 27 C2H2-type zinc fingers

SIAH2 encodes E3 ubiquitin-protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family

Mutations in STK11 have been associated with Peutz-Jeghers syndrome

The protein is able to form a dimer stabilized by noncovalent forces

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents

14-3-3 Beta Polyclonal Antibody, 50ul[BT-AP00004] Roller Bottles Contains 27 C2H2-type zinc fingersYWHAZ (tyrosine 3 monooxygenase tryptophan 5 monooxygenase activation protein zeta) product belongs to the 14 3 3 family of proteins which mediate signal transduction by binding to phosphoserine containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin