EDG-1 Polyclonal Antibody, 50ul[BT-AP02824] Antibody Humanization and it is thought to

and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells

similarity:Belongs to the PPP phosphatase family

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell

Polymorphisms in this gene are associated with type 2 diabetes

EDG-1 Polyclonal Antibody, 50ul[BT-AP02824] Antibody Humanization and it is thought toThe sphingosine 1 phosphate receptor 1 encoded by S1PR1 is structurally similar to G protein coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine 1 phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell cell adhesion. Alternative splicing results in multiple transcript