LIMK-2(Phospho Thr505) Polyclonal Antibody, 20ul Stepper The product of SMAD4 forms

The product of SMAD4 forms homomeric complexes and heteromeric complexes with other activated Smad proteins

The protein encoded by this gene is a secreted

It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases

Mixing these reagents with the cell extract containing luciferase

and is similar to several known polo-like kinase kinases

LIMK-2(Phospho Thr505) Polyclonal Antibody, 20ul Stepper The product of SMAD4 formsThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase