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OVCH2 Rabbit Polyclonal Antibody, 100ul Sample Library Tubes The protein (minichromosome maintenance complex

SKU: 18818297111

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OVCH2 Rabbit Polyclonal Antibody, 100ul Sample Library Tubes The protein (minichromosome maintenance complex

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Description

The protein (minichromosome maintenance complex component 2) encoded by MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication

This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks

Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype

The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex

Mutations in this gene are associated with acromesomelic dysplasia

OVCH2 Rabbit Polyclonal Antibody, 100ul Sample Library Tubes The protein (minichromosome maintenance complex

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