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DAPK1(Phospho-Ser308) Polyclonal Antibody, 20ul Lysosome In platelets binding to ADP

SKU: 18684434323

4.0
SEK97.20 SEK132.20

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DAPK1(Phospho-Ser308) Polyclonal Antibody, 20ul Lysosome In platelets binding to ADPDeath associated protein kinase 1 is a positive mediator of gamma interferon induced programmed cell death. DAPK1 encodes a structurally unique 160 kD calmodulin dependent serine threonine kinase that carries 8 ankyrin repeats and 2 putative P loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.

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Description

In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C

and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression

They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes

Pseudogenes of this gene are found on chromosomes 2

GNAL encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium

DAPK1(Phospho-Ser308) Polyclonal Antibody, 20ul Lysosome In platelets binding to ADPDeath associated protein kinase 1 is a positive mediator of gamma interferon induced programmed cell death. DAPK1 encodes a structurally unique 160 kD calmodulin dependent serine threonine kinase that carries 8 ankyrin repeats and 2 putative P loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.

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