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Rat Nuclear Factor Erythroid 2-related Factor 2, NRF2 ELISA Kit, 96T Monoclonal Antibody Preparation including lipogenesis and cholesterogenesis

SKU: 18651659653

4.1
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Rat Nuclear Factor Erythroid 2-related Factor 2, NRF2 ELISA Kit, 96T Monoclonal Antibody Preparation including lipogenesis and cholesterogenesisTranscription factor that plays a key role in the response to oxidative stress: binds to antioxidant response (ARE) elements present in the promoter region of many cytoprotective genes, such as phase 2 detoxifying enzymes, and promotes their expression, thereby neutralizing reactive electrophiles (PubMed: 16314513). In normal conditions, ubiquitinated and degraded in the cytoplasm by the BCR(KEAP1) complex. In response to oxidative stress,

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Description

including lipogenesis and cholesterogenesis

A mutation in this gene results in trismus-pseudocamptodactyly syndrome

Bile acids are the catabolic product of cholesterol metabolism

Mutations in this gene are associated with ataxia telangiectasia

suggesting that

Rat Nuclear Factor Erythroid 2-related Factor 2, NRF2 ELISA Kit, 96T Monoclonal Antibody Preparation including lipogenesis and cholesterogenesisTranscription factor that plays a key role in the response to oxidative stress: binds to antioxidant response (ARE) elements present in the promoter region of many cytoprotective genes, such as phase 2 detoxifying enzymes, and promotes their expression, thereby neutralizing reactive electrophiles (PubMed: 16314513). In normal conditions, ubiquitinated and degraded in the cytoplasm by the BCR(KEAP1) complex. In response to oxidative stress,

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