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Rat Beta-Arrestin-2, ARRB2 ELISA Kit, 96T Cell Function Analysis Deconjugates SUMO2 from MTA1 (PubMed:

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Rat Beta-Arrestin-2, ARRB2 ELISA Kit, 96T Cell Function Analysis Deconjugates SUMO2 from MTA1 (PubMed:Functions in regulating agonist mediated G protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta arrestins bind to the GPRK phosphorylated receptor and sterically preclude its coupling to the cognate G protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta arrestins target

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Description

Deconjugates SUMO2 from MTA1 (PubMed: 21965678)

Receptor for the heterotrimeric lymphotoxin containing LTA and LTB

Presents to CD8-positive T cells a CMV epitope derived from UL83/pp65 (RCPEMISVL)

and makes up a large portion of endothelial cell intercellular junctions

Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins (PubMed: 15870257

Rat Beta-Arrestin-2, ARRB2 ELISA Kit, 96T Cell Function Analysis Deconjugates SUMO2 from MTA1 (PubMed:Functions in regulating agonist mediated G protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta arrestins bind to the GPRK phosphorylated receptor and sterically preclude its coupling to the cognate G protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta arrestins target

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