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ESX1 Rabbit Polyclonal Antibody, 100ul Peripheral Blood Separation Tube MED13 (mediator complex subunit 13)

SKU: 18013044648

4.2
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ESX1 Rabbit Polyclonal Antibody, 100ul Peripheral Blood Separation Tube MED13 (mediator complex subunit 13)This gene encodes a dual function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N terminal fragment with a paired like homeodomain and a 20 kDa C terminal fragment with a proline rich domain. The C terminal fragment localizes to the cytoplasm while the N terminal fragment localizes exclusively to the nucleus. In contrast to human the mouse homolog has a novel PN PF motif in the C terminus and is paternally imprinted in

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Description

MED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP

Unlike most of the SWI/SNF complex proteins

suggesting a role in tumor development and metastasis

CHP1 encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1

regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth

ESX1 Rabbit Polyclonal Antibody, 100ul Peripheral Blood Separation Tube MED13 (mediator complex subunit 13)This gene encodes a dual function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N terminal fragment with a paired like homeodomain and a 20 kDa C terminal fragment with a proline rich domain. The C terminal fragment localizes to the cytoplasm while the N terminal fragment localizes exclusively to the nucleus. In contrast to human the mouse homolog has a novel PN PF motif in the C terminus and is paternally imprinted in

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