SMD3 Polyclonal Antibody, 20ul Bio-Reaction Tube Mutations in this gene are

Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10)

Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin

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In mammals| the mucolipin family includes 3 members| MCOLN1 (MIM 605248)| MCOLN2| and MCOLN3 (MIM 607400)| that exhibit a common 6-membrane-spanning topology

The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis

SMD3 Polyclonal Antibody, 20ul Bio-Reaction Tube Mutations in this gene areThis gene encodes a core component of the spliceosome, which is a nuclear ribonucleoprotein complex that functions in pre mRNA splicing. Alternative splicing results in multiple transcript variants.