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Histone H4 (Acetyl Lys12) Polyclonal Antibody, 100ul[BT-AP04100] Centrifuge Tube (Bottle) MIM 153240) (summary by Weinreich

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Histone H4 (Acetyl Lys12) Polyclonal Antibody, 100ul[BT-AP04100] Centrifuge Tube (Bottle) MIM 153240) (summary by WeinreichHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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Description

MIM 153240) (summary by Weinreich et al

which are important in RNA binding and are known to be involved in RNA synthesis and metabolism

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication

Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line

CDC2L and SFRS2

Histone H4 (Acetyl Lys12) Polyclonal Antibody, 100ul[BT-AP04100] Centrifuge Tube (Bottle) MIM 153240) (summary by WeinreichHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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