Bag-4 Polyclonal Antibody, 50ul Liquid Storage Consumables signal transduction

signal transduction

tissue specificity:Kidney

This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling| resulting in its dissociation from eIF4E and activation of mRNA translation

Chromosomal translocations involving CREBBP have been associated with acute myeloid leukemia

The expression of the rat gene is upregulated by retinoic acid| which results in a specific reduction in EAAC1-mediated glutamate transport

Bag-4 Polyclonal Antibody, 50ul Liquid Storage Consumables signal transductionThe protein encoded by BAG4 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C terminus, which could bind and inhibit the chaperone activity