Stat1 Polyclonal Antibody, 100ul[BT-AP08615] Primary Antibodies Mutations in this gene have

Mutations in this gene have been associated with two congenital contracture (arthrogryposis) syndromes

This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined

It is highly homologous to the myelin protein zero and| in thymus-derived epithelial cell lines| is poorly soluble in nonionic detergents| strongly suggesting an association to the cytoskeleton

Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family

Genes encoding subunits C| D and E form a cluster on chromosome 3

Stat1 Polyclonal Antibody, 100ul[BT-AP08615] Primary Antibodies Mutations in this gene haveSignal transducer and activator of transcription 1 alpha beta encoded by STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homodimers.