JAK2 mouse Monoclonal Antibody(3F10), 20ul Immune Cell Analysis Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding distinct isoforms have been reported

The sestrin 1 mediates p53 inhibition of cell growth by activating AMP-activated protein kinase

and other cell types

The chromosomal rearrangements are the most common genetic alterations in this gene

and a C-terminal PDZ domain-binding motif

JAK2 mouse Monoclonal Antibody(3F10), 20ul Immune Cell Analysis Alternatively spliced transcript variants encodingThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.