Histone H4 (Di Methyl Lys20) Polyclonal Antibody, 100ul Filtration Interaction with PDCD1 inhibits T-cell

Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production

It encodes a protein with two PHD-type zinc finger domains

shuttling it out of the nucleus and repressing its ability to induce apoptosis

The encoded protein regulates the Catalytic activity of protein phosphatase 1 delta and assembly of the actin cytoskeleton

Overexpression of this gene is associated with glioblastoma

Histone H4 (Di Methyl Lys20) Polyclonal Antibody, 100ul Filtration Interaction with PDCD1 inhibits T-cellHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.