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P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 100ul sgRNA Oligos The proline-rich domain may interact

SKU: 17067382093

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P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 100ul sgRNA Oligos The proline-rich domain may interactThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding

It may also serve as an adapter molecule for the catalytic alpha-subunit

Arrestin beta 2

Alteration of this gene is implicated in the pathogenetics of schizophrenia

It is highly similar to Saccharomyces cerevisiae Cdc14

P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 100ul sgRNA Oligos The proline-rich domain may interactThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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