TLE2 Polyclonal Antibody, 50ul Bio-Reaction Tube The encoded protein is a

The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching

Allelic variants of this gene have been associated with autism and addiction vulnerability

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells

The protein encoded by TNFRSF1A (TNF receptor superfamily member 1A) is a member of the TNF-receptor superfamily

HLA-H displays extensive variation

TLE2 Polyclonal Antibody, 50ul Bio-Reaction Tube The encoded protein is aTransducin like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD repeats implicated in protein protein interaction. TLEs are transcriptional co repressors that bind to many transcription factors such as LEF1, Runx1, Oct 1, hepatocyte nuclear factor 3 as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as