ATG4a Rabbit Polyclonal Antibody, 20ul Protein Post-translational Modification The YTH domain is typical

The YTH domain is typical for the eukaryotes and is particularly abundant in plants

It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation| DNA repair| and/or cell cycle checkpoint control

along with adenylate cyclases 2 and 3

Isoform 1 but not isoform 2 is activated through autoproteolytic processing

apparently by stimulating calcium influx into

ATG4a Rabbit Polyclonal Antibody, 20ul Protein Post-translational Modification The YTH domain is typicalAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene