HPGDS Polyclonal Antibody, 20ul Mini dry bath Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding distinct isoforms have been described

The filaggrin-like protein encoded by this gene is upregulated by calcium| proteolyzed by calpain 1| and is involved in epithelial homeostasis

The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1

and functions as an apoptotic activator

Component of the SCF(SKP2) complex containing SKP2

HPGDS Polyclonal Antibody, 20ul Mini dry bath Two alternatively spliced transcript variantsProstaglandin D synthase is a sigma class glutathione S transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.