p53 Polyclonal Antibody, 20ul[BT-AP06818] 3D Culture and alterations in the expression

and alterations in the expression of their genes are thought to contribute to neoplastic transformation

this kit ensures accurate results every time

It was identified as a gene induced during terminal differentiation in melanoma cells

An important paralog of this gene is AREL1

Two alternatively spliced transcript variants of CDKN2B

p53 Polyclonal Antibody, 20ul[BT-AP06818] 3D Culture and alterations in the expressionTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.