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Jagged1 Polyclonal Antibody, 50ul[BT-AP10553] Microbial Genome Editing This cyclin forms a complex

SKU: 16412204763

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Jagged1 Polyclonal Antibody, 50ul[BT-AP10553] Microbial Genome Editing This cyclin forms a complexThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

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Description

This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6

7-transmembrane receptor) family

The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals

The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D)

two ubiquitous plastin isoforms (L and T) have been identified

Jagged1 Polyclonal Antibody, 50ul[BT-AP10553] Microbial Genome Editing This cyclin forms a complexThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

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