PP4R1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging hypercholesterolemia and insulin-dependent diabetes have

hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19

The encoded protein| a component of the U7 snRNP complex| plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase

May also be involved in the regulation of gene expression

Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration

ADRA2B encodes a seven-pass transmembrane protein

PP4R1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging hypercholesterolemia and insulin-dependent diabetes haveThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.