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IKK gamma(Phospho Ser376) Polyclonal Antibody, 50ul Subcellular Fractions In collagen and related proteins|

SKU: 16254664256

4.1
SEK162.00 SEK206.00

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IKK gamma(Phospho Ser376) Polyclonal Antibody, 50ul Subcellular Fractions In collagen and related proteins|This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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Description

In collagen and related proteins| prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains

Specific isoforms bind to alpha-dystroglycan and to alpha-latroxin

and participate in linking cadherins to intermediate filaments in the cytoskeleton

or by factor VIIa (in the extrinsic pathway)

This gene regulates the activation of nuclear receptors

IKK gamma(Phospho Ser376) Polyclonal Antibody, 50ul Subcellular Fractions In collagen and related proteins|This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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