IGF-IR Polyclonal Antibody, 100ul[BT-AP04399] Tubes The sirtuin 3 encoded by

The sirtuin 3 encoded by SIRT3 is included in class I of the sirtuin family

protein synthesis

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This gene encodes a member of the WWC family of proteins| which also includes the WWC1 (KIBRA) gene product and the WWC2 gene product

IGF-IR Polyclonal Antibody, 100ul[BT-AP04399] Tubes The sirtuin 3 encoded byIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms