PIAS 1 Polyclonal Antibody, 50ul Buffers & Solutions These kinases mediate cellular responses

These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation

and cell death

Mutations in this gene are associated with ectodermal dysplasia

This gene is located on X chromosome in a region containing loci linked to mental retardation

The protein encoded by this gene binds to and is inhibited by dihydropyridine

PIAS 1 Polyclonal Antibody, 50ul Buffers & Solutions These kinases mediate cellular responsesPIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Protein inhibitor of activated STAT 1 plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript