ABCC12 Polyclonal Antibody, 50ul Protein Analysis and studies in mice show

and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease

Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

|subunit:Heterodimer with JUN

Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons

|PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor

ABCC12 Polyclonal Antibody, 50ul Protein Analysis and studies in mice showABCC12 is a member of the superfamily of ATP binding cassette (ABC) transporters and the encoded protein (ATP binding cassette subfamily C member 12) contains two ATP binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR TAP, MRP, ALD, OABP, GCN20, and White. ABCC12 is a member of the MRP subfamily which is