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MDM2 Polyclonal Antibody, 20ul[BT-AP05301] Purification kidney and muscle

SKU: 15486135203

4.3
USD111.00 USD146.00

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MDM2 Polyclonal Antibody, 20ul[BT-AP05301] Purification kidney and muscleMDM2 encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many

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Description

kidney and muscle

as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease

Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes

8kg(O330-M)and speed range 70-400rpm

post-translational processing

MDM2 Polyclonal Antibody, 20ul[BT-AP05301] Purification kidney and muscleMDM2 encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many

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