S10AE Polyclonal Antibody, 20ul Biochemical Reagents Dysregulation of this gene has

Dysregulation of this gene has been associated with the growth and progression of certain cancers

It is primarily an alpha-helical protein with very little coiled coil| and binds directly to the largest subunit (p150) of dynactin

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The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family

S10AE Polyclonal Antibody, 20ul Biochemical Reagents Dysregulation of this gene hasThis gene encodes a member of the S100 protein family which contains an EF hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).