FBX46 Rabbit Polyclonal Antibody, 100ul Molecular Biology This gene encodes the smallest

This gene encodes the smallest subunit of DNA polymerase delta

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands

May be a negative regulator of NF-kappa-B and p53-mediated gene transcription

Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia

GO annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity

FBX46 Rabbit Polyclonal Antibody, 100ul Molecular Biology This gene encodes the smallestMembers of the F box protein family such as FBXO46 are characterized by an approximately 40 amino acid F box motif. SCF complexes formed by SKP1 (MIM 601434) cullin (see CUL1; MIM 603134) and F box proteins act as protein ubiquitin ligases. F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004