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Phospho-4E-BP1 (T69) Polyclonal Antibody, 50ul Gene Synthesis Under hypoxic conditions activates the

SKU: 15086668273

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Phospho-4E-BP1 (T69) Polyclonal Antibody, 50ul Gene Synthesis Under hypoxic conditions activates theEIF4EBP1 encodes one member of a family of translation repressor proteins. The eukaryotic translation initiation factor 4E binding protein 1 directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is

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Description

Under hypoxic conditions activates the transcription of over 40 genes| including| erythropoietin| glucose transporters| glycolytic enzymes| vascular endothelial growth factor| and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia

The protein localizes to the outer membrane of mitochondria

The consequence of CD5 binding to its cognate receptor is still in question and likely plays a role in thymic selection

medical diagnosis

In late G2 the protein associates with the kinetochore and maintains this association through early anaphase

Phospho-4E-BP1 (T69) Polyclonal Antibody, 50ul Gene Synthesis Under hypoxic conditions activates theEIF4EBP1 encodes one member of a family of translation repressor proteins. The eukaryotic translation initiation factor 4E binding protein 1 directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is

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