SLIK5 Polyclonal Antibody, 20ul Thermo Mix Receptor tyrosine-protein kinase erbB-2 has

Receptor tyrosine-protein kinase erbB-2 has no ligand binding domain of its own and therefore cannot bind growth factors

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Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage

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The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L)| which suggests the antiapoptotic function of this gene in cells

SLIK5 Polyclonal Antibody, 20ul Thermo Mix Receptor tyrosine-protein kinase erbB-2 hasMembers of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N terminal leucine rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite modulating activity (Aruga et al., 2003