Histone H4 (Acetyl Lys12) Polyclonal Antibody, 100ul[BT-AP04099] Reagent Reservoirs Mutations in LMNA lead to

Mutations in LMNA lead to several diseases: emery-Dreifuss muscular dystrophy

Among its related pathways are Gene Expression and Cell Cycle

Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18

The protein encoded by UGDH (UDP-glucose 6-dehydrogenase) converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan

which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes

Histone H4 (Acetyl Lys12) Polyclonal Antibody, 100ul[BT-AP04099] Reagent Reservoirs Mutations in LMNA lead toHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.